الفهرس 
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Abstract
pRES has been increasingly recognized within the cancer population. There are several chemotherapeutic agents have been associated with PRES.
Although PRES was originally described in association with HTN. It has been also described with a variety of systemic conditions, including autoimmune diseases, septic shock, and chemotherapy.
Nowadays awareness of PRES is increasing as a complication of chemotherapy particularly in pediatric oncology, but it still less frequently recogonized in adult oncology, and suspecting this condition early when there are neurological changes and the above-mentioned risk factors is important to avoid potential, nonreversible complications.
PRES has various non specific Symptoms but most commonly presented with seizures as well as altered mental status, headache and visual changes.
The aim of our study is to evaluate the role of MR radiological features of PRES in cancer patients and to emphasize the recognition of atypical patterns.
Brain MRI is considered the most important diagnostic tool for early diagnosis and follow-up of patients with PRES . The typical pattern is relatively symmetrical cortical/ subcortical white matter edema in parieto-occipital regions of both cerebral hemispheres.
It also found that atypical regions of involvement and atypical MR patterns like areas with asymmetry, restricted diffusion, hemorrhage and contrast enhancement were found to be more common than generally perceived.
Our study suggests a significant association between high grades of edema and the poor clinical outcome and brings value to the use of an MR imaging grading scale in the prognosis of patients with PRES to estimate its reversibility.
Regarding to clinical outcome of the disease our study revealed that the majority of PRES patients were found to be completely reversible, even with restricted diffusion and those who died were due to existence of concomitant comorbidities at the time of the diagnosis of PRES