الفهرس 
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Abstract
Skin diseases are among the most common health problems in dogs and cats. The study aimed to survey some dermatological disorders in patients who come to veterinary clinics through clinical examination of the diseased animals, laboratory examination of different samples taken from diseased animals to define accurately the disease problems, determination some oxidative stress indices aiming to detect the effect of the studied skin diseases on their levels in blood plasma of affected animals. The clinical study was conducted on two groups of dogs and cats. The first one was the diseased included ninety dogs and forty cats of different ages. The second group was clinically healthy fourteen dogs and 5 cats were used as a control group. The diseased group was classified according to etiology into dermatophytosis, mange, pyoderma, atopic dermatitis, flea allergic dermatitis, tick infestation and ear mites groups. Animals were subjected to physical examination followed by special dermatological examination. Skin scraping and ear swapping samples were examined under microscope for detection of mites and fungal spores. Blood samples were taken for hematological analysis for complete blood picture and for biochemical analysis of zinc, Cu and oxidative stress markers including catalase, SOD, GPx and MDA. Significant differences in hematological parameters were observed in all diseased groups. Furthermore, Oxidative stress markers such as catalase, SOD, GPx and MDA revealed significant variations in all diseased groups when compared to healthy ones. Correlation analysis revealed positive correlation between plasma zinc and copper levels and antioxidant enzymes as SOD, GPx and negative correlation between them and plasma MDA levels.