الفهرس | Only 14 pages are availabe for public view |
Abstract Summary Asthe liver is the largest and most important metabolic organ, it plays a pivotal role in integrating several biochemical pathways of carbohydrate, fat, protein, and vitamin metabolism.Various metabolic changes may occur in end-stage liver disease (ESLD) patients as insulin resistance, depletion of glycogen stores, increase in protein catabolism, imbalance of branched chain amino acids (BCAA) and aromatic amino acids, deficiency of essential fatty acids and poly unsaturated fatty acids So, the prevalence of malnutrition has been reported in a significant proportion of patients with cirrhosis and ranges from 10% to 100%, contingent on the severity of hepatic decompensation in the setting of cirrhosis and it’s related outcomes have been recognized with many studies that show the negative impact after LDLT, such as longer hospital and intensive care unit stay, graft impairment, infections up to mortality. Nutritional status is considered as one of the variables that are highly correlated with patient’s survival, also it is not dependent solely on the disease status, and therefore it is potentially reversible. Thus, interdisciplinary teams should definitely prioritize nutritional therapy as an integral part of liver transplant care considering the difficulties in nutrition status assessment among ESLD patients by using different nutritional assessment methods. |