الفهرس 
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Abstract
Erectile dysfunction is defined by the Fourth International
Consultation on Sexual Medicine as the consistent or recurrent
inability to attain and/or maintain penile erection sufficient for sexual
satisfaction.
Normal sexual function has been described as a biopsychosocial
Process that involves the coordination of psychological, endocrine,
vascular, and neurological systems. Erectile dysfunction is classified
as psychogenic, organic (i.e., neurogenic, hormonal, arterial,
cavernosal, or drug-induced), or mixed psychogenic and organic.
Erectile dysfunction is usually of a mixed psychogenic and organic
nature.
Risk factors for ED include age, diabetes, hypertension, obesity,
lack of exercise, dyslipidemia, smoking, depression, lower urinary
tract symptoms, and pelvic surgery.
Melatonin is the main hormone secreted by the pineal gland. It
is mainly synthesized by the pinealocytes from the amino acid
tryptophan
Melatonin received much attention from researchers in the last
decades and apart from being an inducer of sleep, many other vital
functions were discovered. One of these is the regulation of the
hypothalamo-pituitary-gonadal axis. It was proved that; its elevation
causes inhibition of the whole axis. Its exact role in ED is unclear and
very little researches exist.
So, we aimed by this work to spotlight on its relation to ED
through measuring its level and to find out its correlation with clinical
data.
This case control study included 60 patients with erectile
dysfunction and 30 age-matched healthy controls. After taking history
and doing a clinical examination, we measured melatonin, CBC, ALT,
AST, HbA1c, TT, FT, and Prolactin.