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العنوان
Prognostic markers for facial nerve function and hearing preservation in microsurgical resection of vestibular schwannomas/
المؤلف
Elsayed, Mohamed Ahmed Magdieldin.
هيئة الاعداد
مشرف / هاني فاروق الجارم
مشرف / أوليفير ستيركيرز
مشرف / ياسمين علي الاشرم
مناقش / مختار عبد الخالق بسيونى
الموضوع
Otorhinolaryngology.
تاريخ النشر
2021.
عدد الصفحات
34 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الحنجرة
تاريخ الإجازة
10/6/2021
مكان الإجازة
جامعة الاسكندريه - كلية الطب - Department of Otorhinolaryngology
الفهرس
Only 14 pages are availabe for public view

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from 81

Abstract

The aims of surgery in the cerebellopontine angle (CPA) have changed from tumor resection and prolongation of life to the anatomical and functional preservation of the cranial nerves. Facial palsy is one of the most serious morbidities because loss of facial expression is a functionally and psychologically debilitating condition. It is a debilitating condition that may lead to difficulties in several areas of daily life, including speaking, eating, and blinking (which may lead to dry eyes and corneal damage).
Anatomical and functional preservation of FN in VS surgery is still challenging even for experienced neurosurgeons. In large VS cases, FNs are always displaced and morphologically changed in an unpredictable manner. Some are even indistinguishable from the tumor capsule under microscope. There have no models for predicting FN course in VS cases so far. The main purpose of intraoperative monitoring is to make the surgical team aware of the ongoing changes in the neural function, thereby permitting modifications in surgical strategies that can ultimately avoid neural damage.
For the purpose of risk minimization, a monitoring system is required that continuously monitors the integrity of nerve function during the operation. Continuous intraoperative neuromonitoring (C-IONM) affords close monitoring in real time of the functional integrity of the entire facial so that impending nerve injury can be detected on time, enabling quick corrective action.
A clinical prospective study was performed of patients who were operated for microsurgical resection of VS with anatomic preservation of the facial nerve. The primary goal of this study was to identify the clinical peri-operative factors that could determine the occurrence of an immediate postoperative impaired facial function and recovery in the long-term. Secondarily, to refine the predictive value of intraoperative monitoring, we thought it would be interesting to investigate FN monitoring parameters (i.e. pre- and post-surgical resection ratios of amplitude and latency values at supra-maximal stimulation) to determine if either value could prognosticate FN outcome.