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العنوان
Impact of Dexamethasone Added To Intra-
Articular Morphine and Bupivacaine for
Post-Operative Analgesia after Knee
Arthroscopy /
المؤلف
Abd El-Aziz, Amr Mohammed Talaat.
هيئة الاعداد
باحث / عمرو محمد طلعت عبد العزيز
مشرف / رأفت عبدالعظيم حماد
مشرف / أحمد عبدالدايم عبدالحق
مناقش / هبة فؤاد عبدالعزيز طولان
تاريخ النشر
2021.
عدد الصفحات
114p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب (متفرقات)
تاريخ الإجازة
1/1/2021
مكان الإجازة
جامعة عين شمس - كلية الطب - التخدير
الفهرس
Only 14 pages are availabe for public view

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Abstract

SUMMARY
his study was carried out in Ain Shams University
Hospital and included 40 patients of both sexes
undergoing minor knee arthroscopy operation under
general anesthesia
The aim of the study was to evaluate the effect of adding
dexamethasone (8mg) to intra -articular morphine (10mg) and
bupivacaine (25mg) injection on postoperative pain after knee
arthroscopy.
Patients were randomly allocated into two equal groups, (20
patients in each group) according to the medications they had
received by intra-articular injection at the end of surgery:
group I (control, M group):
10mg morphine in 5ml normal saline + 10ml of 0.25%
bupivacaine (total volume 15 ml) were injected intraarticularly.
group II (study, MD group):
10mg morphine + 8mg dexamethasone completed to 5
ml with normal saline + 10 ml of 0.25 % bupivacaine (total
volume of 15ml) were injected intra-articularly.
Pain at rest and movement was assessed by VAS at the
following post-operative periods: on admission to the post
anesthesia care unit when the patient is fully conscious and at 2,
T
Summary 
83
4, 6, 8, 10, 12, 18, 24 h post operatively with observation of
hemodynamics.
Time of first analgesic request (associated with VAS ≥
4), total consumption of supplemental analgesia over 24h and
occurrence of compilcations or adverse effects was recorded.
The main finding in this study was that adding
dexamethasone to intra articular morphine bupivacine
combination after minor knee arthroscopies resulted in
prolonged analgesia, lower VAS for pain at rest and at
movement and decreased total analgesic consumption.
The VAS for pain at rest was significantly lower in MD
group than M group at recovery, 2hr, 4hr, 6hr, 8hr, 10hr, 12hr
and 18hr post operatively and there was no significant
difference between the two groups at 24hr post operatively.
The VAS for pain at movement was significantly lower in
MD group than M group at recovery, 2hr, 8hr, 10hr, 12hr and
18hr post operatively and there was no significant difference
between the two groups at 4hr, 6hr and 24hr post operatively.
The mean time for first analgesic request was (9.50 ± 1.71)
in control group while it was (12.50 ± 3.66) in study group.
The amount of total analgesic consumption was
significantly more in control group than the study group.
There were no complications or adverse effects observed
in both groups.