الفهرس | Only 14 pages are availabe for public view |
Abstract SUMMARY his study was carried out in Ain Shams University Hospital and included 40 patients of both sexes undergoing minor knee arthroscopy operation under general anesthesia The aim of the study was to evaluate the effect of adding dexamethasone (8mg) to intra -articular morphine (10mg) and bupivacaine (25mg) injection on postoperative pain after knee arthroscopy. Patients were randomly allocated into two equal groups, (20 patients in each group) according to the medications they had received by intra-articular injection at the end of surgery: group I (control, M group): 10mg morphine in 5ml normal saline + 10ml of 0.25% bupivacaine (total volume 15 ml) were injected intraarticularly. group II (study, MD group): 10mg morphine + 8mg dexamethasone completed to 5 ml with normal saline + 10 ml of 0.25 % bupivacaine (total volume of 15ml) were injected intra-articularly. Pain at rest and movement was assessed by VAS at the following post-operative periods: on admission to the post anesthesia care unit when the patient is fully conscious and at 2, T Summary 83 4, 6, 8, 10, 12, 18, 24 h post operatively with observation of hemodynamics. Time of first analgesic request (associated with VAS ≥ 4), total consumption of supplemental analgesia over 24h and occurrence of compilcations or adverse effects was recorded. The main finding in this study was that adding dexamethasone to intra articular morphine bupivacine combination after minor knee arthroscopies resulted in prolonged analgesia, lower VAS for pain at rest and at movement and decreased total analgesic consumption. The VAS for pain at rest was significantly lower in MD group than M group at recovery, 2hr, 4hr, 6hr, 8hr, 10hr, 12hr and 18hr post operatively and there was no significant difference between the two groups at 24hr post operatively. The VAS for pain at movement was significantly lower in MD group than M group at recovery, 2hr, 8hr, 10hr, 12hr and 18hr post operatively and there was no significant difference between the two groups at 4hr, 6hr and 24hr post operatively. The mean time for first analgesic request was (9.50 ± 1.71) in control group while it was (12.50 ± 3.66) in study group. The amount of total analgesic consumption was significantly more in control group than the study group. There were no complications or adverse effects observed in both groups. |