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Abstract that is sufficient to warrant a change in therapy. Management of AE-COPD is through medical treatment only or combined with positive pressure ventilation.Noninvasive ventilation recently becomes a gold standard for COPD management that improves oxygenation and ventilation and decrease work of breathing. As a result, it improve the patient prognosis, relieve patient dyspnea and decrease the need for intubation. The aim of this study is to compare between the two scores (BAP 65/DECAF) in assessment of patient with COPD exacerbation. This study included 50 patients who were admitted to the chest department or ICU Menoufia University with acute exacerbation of COPD. All patients were subjected to full history taking, complete medical examination and thorough laboratory and radiological investigations. Then treated either medically or with NIPPV/IMV. Both DECAF and BAP-65 scores performed well for prediction of in-hospital mortality with 100% Sensitivity for both scores while the specificity was 87% and 91% for DECAF score and BAP-65 score respectively. The accuracy in prediction of mortality for DECAF and BAP65 score was 88% and 92% respectively. Sensitivity of DECAF and BAP-65 scores for prediction of MV need was 93% and 87% respectively, while the specificity was 74% and 60% respectively, with 80% accuracy in DECAF score and 68% accuracy in BAP65 score. There was a positive linear relationship between DECAF score and BAP-65 score on Pearson’s graph with a significant correlation (r = 0.604, P < 0.001). Summary 83 In this study, both BAP65 and DECAF scores revealed a significant relation with need for IMV and mortality rate in patients with AECOPD. Finally, early escalation in treatment and good monitoring of COPD exacerbation should be followed in high risk scored patients. |