الفهرس 
Anatomy of the Upper Respiratory System.Only 14 pages are availabe for public view
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Abstract
Background: Postoperative sore throat and hoarseness of voice are common
complications following endotracheal intubation for general anaesthesia. These
adverse events may have a negative effect on patients’ satisfaction and activities
after surgery. The objective of the current study is to evaluate the efficacy of
inhalation of budesonide Vs intravenous Dexamethasone in reducing the incidence
of postoperative sore throat and hoarseness of voice in patients undergoing elective
surgery under general anaesthesia.
Methods: This is a comparative randomized clinical study performed in Faculty
of Medicine, Fayoum University on 120 patients ASA I and II patients scheduled
for an elective surgery with tracheal intubation under general anaesthesia. Pre-
anesthesia evaluation was performed and then selected patients was divided into three
groups each group include 40 patients, group (A) inhalational budesonide group,
group (B) intravenous dexamethasone group and group (C) Control group. At the
end of surgery, Patients were transferred to postoperative anesthesia care unit
(PACU) with standard monitoring applied. Outcome assessment for the incidence
of sore throat and hoarseness was carried out at 1, 6, 12 and 24 hours post-
extubation
Results: There was no statistically significant difference between the three
groups regarding their sex, age, weight, height and BMI. Sore throat was
significantly lower in the dexamethasone group than the budesonide group and the
control group after one and six hours and it was continuing to be low but with no
statistical significance after twelve and twenty four hours. Hoarseness of voice was
significantly lower in the dexamethasone group than the budesonide group and the
control group after six hours only and it was continuing to be low but with no
statistical significance after twelve and twenty four hours.
Conclusions: This study revealed that the incidence and severity of post-
operative sore throat and hoarseness of voice were lower in patients received IV
dexamethasone than those treated with budesonide by inhalation prior to induction
of anaesthesia with comparable results in relation to the risk factors as BMI,
number of intubation attempt , time to achieve intubation and duration of the
procedure.
Abstract
Keywords: Sore throat – Hoarseness of voice – Budesonide – Dexamethasone.