الفهرس 
Chapter I:Physiology of The Coronary CirculationOnly 14 pages are availabe for public view
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Abstract
Primary PCI is the preferred reperfusion strategy used in patients with acute STEMI to prevent progression of myocardial necrosis. Besides the advantages of this strategy, there are situations in which myocardial reperfusion is not restored to its optimal level.
Angiographic no-reflow phenomenon, a reduced coronary antegrade flow (TIMI flow grade ≤ 2) without mechanical obstruction after recanalization, predicts poor LV functional recovery and survival in the early phase of STEMI1.
The no-reflow phenomenon is critical and, if not reversed, causes a high rate of morbidity and mortality. It was demonstrated that the no-reflow phenomenon after primary PCI is a strong predictor of death extending to up to 5 years after the acute event in patients with STEMI.
Although the predisposing factors of the no-reflow phenomenon were investigated, there is little data about clinical and procedural predictors of this phenomenon.
The aim of this study was to evaluate the levels of oxidative stress markers as a predictor of no-reflow in patients who underwent primary percutaneous intervention.
The present study was conducted on 90 patients admitted with STEMI and treated with 1ry PCI at cardiovascular medicine department at Naser institute Hospital within 24 months started from June 2017. Patients were divided into 2 groups according to no-reflow phenomenon. group 1 consisted of 45 patients that had no-reflow phenomenon & group 2 consisted of 45 patients that had normal flow after primary PCI.
Summary
The two groups were studied regarding demographic data, prevalence of risk factors, clinical characteristics, lesion characteristics, type of stents used, LV systolic function and oxidative stress markers in both groups. The results were statistically analyzed and discussed. There was statistically significant difference between the two groups regarding the oxidative stress markers that can be used as predictors of No-reflow phenomena in patients with STEMI before revascularization.