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Abstract This case control study was conducted at Department of family planning at Al Shohadaa Hospital in the period between December 2018 and January 2020. The population of this study was non-pregnant women who attended family planning clinic and requested an IUCD insertion aged 18–45 years and delivered before by only elective caesarean section. The study included 96 women who fulfilled inclusion criteria. They were subjected to full history taking and physical and local examination then they were randomized by shuffling technique (ratio 1:1) into 2 groups each of them had 48 women. group A included 48 women received 400 μg misoprostol; 2 tablets vaginally of (Misotac® 200 μg, Sigma Ph., Egypt) three hours before IUCD insertion and lignocaine spray (Manoviperacaine® 10% mg, EVA PHARMA, Egypt) three puffs to the cervical surface and one puff to the external cervical os 3 minutes before IUCD insertion. group B (control group) included 48 women did not receive any medical intervention. IUCD was inserted to women in lithotomy position, Patients were observed for 30 minutes after the procedure. Patients were asked to rate their pain level on two different levels (immediately after grasping the cervix with the vulsellum and after sounding the uterus and insertion of the IUCD). Assessment of pain on those two levels was made on a modified continuous 10-cm Visual analogue scale (VAS) to quantify the pain, from 0 cm (no pain) to 10 cm (the worst pain ever). This case control study assessed the efficacy and safety of vaginal misoprostol and lignocaine spray before IUCD insertion. Summary 65 Statistical analysis of the current study showed that combined use of vaginal misoprostol and lignocaine spray had led to reduction in pain scores during sounding the uterus and during IUCD insertion, however, there were no significant statistical difference between two groups regarding the pain during grasping the cervix with vulsellum. Also, the current study had shown that the duration needed for IUCD insertion was lesser in group A than group B, moreover the uterine length by sound was significantly shorter in group A than group B. Although the pain scores during IUCD insertion were lower in group A, there was no significant statistical difference between both groups regarding insertion result (failed, easy or difficult insertion) and complications (No complication, post insertion bleeding or post insertion pain). |