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Abstract Background: Breast cancer is the most common cancer in women worldwide, with nearly 1.7 million new cases diagnosed only in 2012 (second most common cancer overall). This represents about 12% of all new cancer cases and 25% of all cancers in women. Cancer care has become more individualized for patients, and thus, better characterization for treatment planning is required. Sono-mammography has been widely used but due to its low sensitivity, other methods were required, and biopsy was needed as the gold standard test. A newly introduced MRI sequence DWIBS allows the acquisition of volumetric diffusion weighted images with high lesion-to-background contrast, hence making the use of contrast material unnecessary and thought to decrease the rate of unnecessary biopsies Results: In our study the selected patients underwent both dynamic contrast enhanced MRI technique (DCE) & Diffusion weighted imaging with background signal suppression (DWIBS). DWIBS found to be better than DCE in its sensitivity and negative predictive value; measuring 97.47% and 95.24%, compared to 94.7% and 91.7% respectively, yet DCE showed higher specificity and PPV measuring 95.7% and 97.39% compared to 87% and 92.5% for DWIBS respectively. DWIBS valuable role was assessed in terms of its higher ability than DCE to detect the lesions correlated with the histopathological findings where DWIBS could detect 97.47% of the lesions included in our study, on the other side DCE detected 94.7% of the lesions. Conclusion: In our study, we found that DCE-MRI and DWIBS showed comparable results as regards to their sensitivity and specificity. DWIBS however showed higher sensitivity and negative predictive value than DCE , thus it can be very useful screening tool without the need for a lengthy MRI procedure or the need for IV contrast administration. |