الفهرس | Only 14 pages are availabe for public view |
Abstract While fluorescein angiography is still considered the gold standard for imaging retinal vasculature in vivo, OCTA is a non-invasive, relatively fast imaging study that can be performed alongside routine OCT imaging. Several studies have demonstrated its applicability in diabetic patients. OCTA allowed the study of the retinal vascular bed and discriminates between superficial and deep retinal vascular plexuses, which cannot be represented by conventional fluorescein angiography. OCTA demonstrated the ability to provide critical information about vascular changes in varying stages of Diabetic Retinopathy. It also allows screening for DR, and assessment of disease severity. Using the OCTA machine with AngioAnalytics parameters (vessel area density and non-flow area) aided in the objective quantification of macular perfusion and accurate measurement of the FAZ area in diabetic eyes with and without macular edema. Both parameters were significantly correlated with visual function in treatment-naive diabetic eyes with macular edema. OCTA demonstrated an enlargement of the FAZ area and a reduction in retinal capillary density in the SCP and DCP in eyes with DR. Our findings highlight the potential role of OCTA in monitoring and quantifying retinal vascular alterations in diabetes. OCTA study of areas of nonperfusion in CME showed that cystoid spaces were spatially overlapped within areas of capillary nonperfusion and proven that in early stages of untreated CME there is a strong relationship between the occurrence of edema and the capillary dropout. OCTA provided images with greater detail regarding macular status and may become a novel imaging technique for the diagnosis of DMI. |