الفهرس 
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Abstract
While fluorescein angiography is still considered the gold standard
for imaging retinal vasculature in vivo, OCTA is a non-invasive, relatively
fast imaging study that can be performed alongside routine OCT imaging.
Several studies have demonstrated its applicability in diabetic patients.
OCTA allowed the study of the retinal vascular bed and discriminates
between superficial and deep retinal vascular plexuses, which cannot be
represented by conventional fluorescein angiography.
OCTA demonstrated the ability to provide critical information about
vascular changes in varying stages of Diabetic Retinopathy. It also allows
screening for DR, and assessment of disease severity.
Using the OCTA machine with AngioAnalytics parameters (vessel
area density and non-flow area) aided in the objective quantification of
macular perfusion and accurate measurement of the FAZ area in diabetic
eyes with and without macular edema. Both parameters were significantly
correlated with visual function in treatment-naive diabetic eyes with macular
edema.
OCTA demonstrated an enlargement of the FAZ area and a reduction
in retinal capillary density in the SCP and DCP in eyes with DR. Our
findings highlight the potential role of OCTA in monitoring and quantifying
retinal vascular alterations in diabetes.
OCTA study of areas of nonperfusion in CME showed that cystoid
spaces were spatially overlapped within areas of capillary nonperfusion and
proven that in early stages of untreated CME there is a strong relationship
between the occurrence of edema and the capillary dropout.
OCTA provided images with greater detail regarding macular status
and may become a novel imaging technique for the diagnosis of DMI.