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Abstract Background: Retained sputum conflicts the weaning trial, as well as increase the risk of chest infection and prolong the time on mechanical ventilation Objective: To evaluate the impact of using mechanical exsufflators insufflators as cough augmentation technique on outcome of weaning, in addition to assessing the rate of successful weaning using NIV and T-tube mode. Methods: A randomizes control trial that included 15 patients in two limbs; the first weaned by NIV mode, the second by T-tube mode. All patients prepared equally for spontaneous breathing trial (SBT), and using ME-I frequently just before SBT. Results: The rate of successful weaning in all cases was 66.6% (20 patients of 30), the rate was higher in groups that weaned by T-tube than NIV mode (86.67% versus 46.67%), P = 0.01. Moreover, the number of ME-I cycle was significantly higher in group with successful weaning than other group, P = 0.02.In addition, the ventilation support time was significantly longer in failed group than the successful one, P < 0.001. Conclusion: The use of MI-E just before the weaning trial enhance the outcome of weaning, moreover, the weaning trial by T-tube mode gave a higher successful rate during spontaneous breathing trial (SBT). |