الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 121 |  |  |
| | | from | 121 | | |
Abstract
Background: End-tidal carbon dioxide (ETCO2) measurement is more applied in clinical practice, as it is a noninvasive tool that helps to evaluate the ventilatory status of the patient. The aim of the present study was to investigate the relationship between ETCO2 and arterial partial pressure of CO2 (PaCO2) measurements and to estimate the role of capnography during weaning off mechanical ventilation. Patients and methods: A prospective cross-sectional study was conducted on 60 adult critically ill patients with respiratory failure, comprising 47 males and 13 females. They were put on mechanical ventilation, and after fulfilling criteria of weaning, they were kept on continuous positive airway pressure (CPAP) mode for 1h. ETCO2, PaCO2, and gradient were measured before and after weaning. Results: Mean difference between PaCO2 and ETCO2 before weaning was 8.3 and after one hour on CPAP was 5.1. There was a highly statistically significant positive correlation between ETCO2 and PaCO2 before weaning and after 1h on CPAP. Bland-Altman comparison between ETCO2 and PaCO2 before weaning and after 1h on CPAP revealed limits of agreement were 1.941 to 14.826 and −4.134 to 14.367, respectively. Conclusion: ETCO2 measurement gives a proper estimation of PaCO2 in patients on mechanical ventilation. ETCO2 decreases the need for repeated invasive arterial blood gas samples.