الفهرس 
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Abstract
Periodontal disease is an inflammatory disease of the periodontium
characterized by progressive destruction of the tissues supporting the
tooth, the aim of periodontal treatment is to arrest the progressive
destruction of the periodontal tissues and to restore them to a healthy state
which the patient can maintain.
Although periodontal disease is a multifactorial infectious disease,
microbial plaque is recognized as the primary etiologic agent for
initiation and progression of the disease. chronic periodontal disease can
be successfully treated by non-surgical or surgical mechanical therapy
provided adequate plaque control is maintained during the supportive
phase of treatment.
The present investigation was conducted to evaluate clinically and
radiographically the effect of vitamin C (ascorbic acid), vitamin E and
Zinc on chronic periodontitis patients.
The study was performed on twenty male medically free patients
having chronic periodontitis. Radiographic bone density evaluation, the
clinical parameters which included; plaque index, gingival index, probing
depth and clinical attachment loss as well as gingival crevicular fluid
samples to be examined for matrix metalloproteinase (MMP8) were
recorded at baseline, one and three months.