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العنوان
Delayed post contrast fluid-attenuated inversion recovery (flair) sequence versus post contrast t1 sequence in the diagnosis of metastatic brain diseases/
المؤلف
Abdel Rahman, Shaimaa Ali.
هيئة الاعداد
باحث / شيماء علي عبد الرحمن
مناقش / محمد سامى أحمد بركات
مناقش / عبد العزيز محمد النقيدي
مشرف / رفيق محمد ابراهيم
الموضوع
Radiodiagnosis. Interventional radiology.
تاريخ النشر
2020.
عدد الصفحات
66 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
5/1/2021
مكان الإجازة
جامعة الاسكندريه - كلية الطب - Radiodiagnosis and Intervention Radiology
الفهرس
Only 14 pages are availabe for public view

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Abstract

The purpose of this study was to evaluate the role of delayed post-contrast FLAIR, in comparison to post-contrast T1, in the detection and evaluation of brain metastases.
The study was conducted on 40 patients with suspected/known brain metastases scanned in order to detect and evaluate brain metastases.
All patients were subjected to the following: Full history taking, review of clinical examination reports, and other imaging modalities whenever available, followed by brain MRI examination using: Philips Ingenia 1.5 tesla.
This study included 18 males and 22 females, ranging in age from 26 to 75 years. Six out of a total of 40 patients had brain metastases of unknown origin while 34 of them were presented with different types of known primary tumors.
The detected lesions were subdivided into five groups according to their detectability by delayed post-contrast FLAIR and post-contrast T1WI:
1. group (I): Lesions detected only by delayed post-contrast FLAIR: 16 lesions.
2. group (II): Lesions detected only by CE-T1WI: One lesion.
3. group (III): Lesions detected by both delayed post-contrast FLAIR and CE-T1WI with equal conspicuity by both: 28 lesions.
4. group (IV): Lesions detected by both, showing more obvious enhancement with delayed post-contrast FLAIR: 43 lesions.
5. group (V): Lesions detected by both, showing more obvious enhancement with CE-T1WI: 11 lesions.
Delayed post-contrast FLAIR had a sensitivity of 98.98% and a specificity of 100% for the detection of metastatic brain lesions and for post-contrast T1 sensitivity of 83.83% and a specificity of 50%.
In this study delayed post-contrast FLAIR is considered a reliable sequence for the detection of metastatic brain lesions. It gives a more confident evaluation of metastatic brain lesions, as some lesions detected with delayed post-contrast FLAIR could not be detected by CE-T1WI, and some lesions are more evident on delayed CE-FLAIR than CE-T1WI.