الفهرس 
Multiple SclerosisOnly 14 pages are availabe for public view
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Abstract
Encourage the adequate adherence to medications that helps introducing new line of treatment when needed in order to decrease the rate of relapses and the disability to improve the QoL of MS patients. Spread awareness about the MS disease among the population. We may need further research to demonstrate the role of education in the chronic disease and its impact on the QoL. We have to encourage the MS patient to have a job and to facilitate the conditions to be committed to their work. Eencourage the MS patient who smokes to quit, and to introduce programmes for smoking cessation in order to enhance the psychological impact and to improve the QoL of MS patients.
Quality of Life (QOL) is impaired in multiple sclerosis (MS) in part due to physical disability. MS-associated fatigue (MSF) and depression (MSD) are common and treatable features of MS, which could also impact on QOL, independent of physical disability. We prospectively studied 60 consecutive patients with MS. QOL was assessed using Multiple Sclerosis Quality of Life (MSQOL)-54. group differences in QOL scores were assessed after adjusting for Expanded Disability Status Scale (EDSS), Fatigue Severity Scale (FSS) and Hamilton Depression Inventory scores. MS patients were grouped into relapsing–remitting (RR) or secondary-progressive (SP), MSF (FSS≥5) or MS-nonfatigue (MSNF) (FSS≤4), and MSD or MS-nondepression (MSND). After accounting for disability and depression, fatigue was associated with impaired QOL with respect to health perception (p=0.03) and limitations due to physical dysfunction (p=0.008). After accounting for disability and fatigue, depression was associated with lower QOL with respect to health perception (p=0.02), sexual dysfunction (p=0.03), health distress (p=0.03), mental health (p=0.006), overall QOL (p=0.006), emotional dysfunction (p=0.04), and limitations due to emotional dysfunction (p=0.03). This study demonstrates that fatigue and depression are independently associated with impaired QOL in MS, after accounting for physical disability, suggesting that their recognition and treatment can potentially improve QOL.