الفهرس 
Chapter 1: characterization and biological evaluation of bee breadOnly 14 pages are availabe for public view
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Abstract
The scientific output of the current thesis revealed the various beneficial therapeutic properties of bee bread. Bee bread is a byproduct fermented mixture of bee pollen, nectar and bee saliva extensively used safely in traditional medicine as a dietary supplement. This study intended to evaluate the anti-inflammatory and antioxidant potential of bee bread extracts to support its beneficial effects. The antioxidant activity of n-hexane, ethanol and ethanol-water extracts of bb was determined against DPPH radical and lipid peroxidation with the avail of UV spectrophotometer at 517 nm and 532, respectively. The ethanol extract showed most potent activity for all extract concentrations tested. The anti-inflammatory potential was evaluated by carrageenan of experimentally induced inflammation in rats. The results estimated a significant production in edema formation in the paw treated with carrageenan as compared to control at low concentrations. In the group of basic chemical substances of bb evaluated by 1H-NMR and 13C-NMR, there are fatty acids and glycerides.
On the other hand, another study was done to synthesize a series of novel thiazoles derivatives in one step methodology with good yields by reaction of 2-(1-(2-(2-(benzylidene)hydrazinyl)-4-methylthiazol-5-yl)ethylidene)hydrazine-1-carbothioamide with each of N-phenyl 2-oxopropanehydrazonoylchloride and ethyl (N-aryl-hydrazono) chloroacetate in dioxane in basic medium. Another series of product 2-(2-(benzylidene)hydrazinyl)-5-(1-(2-(4-(phenyl)thiazol-2-yl)hydrazono)ethyl)-4-methylthiazole was prepared by the reaction of the start with each of phenathylbromide under the same reaction conditions. The assigned structures for all the newly synthesized compounds were confirmed on the basis of elemental analyses and spectral data (IR, NMR, and MS) and the mechanisms of their formation were also discussed. Moreover, the anticancer activity for all products was screened, and the results obtained exploring the promising potency of some of the tested compounds compared with the employed standar.