الفهرس 
Neonatal hyperbilirubinemiaOnly 14 pages are availabe for public view
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Abstract
Background: Phototherapy though safe, is not free of side effects. Most
of the studies have documented thrombocytopenia as a result of phototherapy.
However, few other studies have proven the opposite effect.
Objectives: To evaluate the effect of phototherapy on the platelet count in
neonates with non- hemolytic indirect hyperbilirubinemia.
Materials and Methods: A prospective cohort study which involved 120
neonates, who developed indirect hyperbilirubinaemia and required
phototherapy during a period of six months from December 2018 to May 2019.
Neonates having a base line platelet count of more than 150,000/mm3 were
included .Platelet counts were performed on admission, before discontinuing
phototherapy and one week later for those how developed thrombocytopenia.
Results: Out of 120 neonates included in study, 9 neonates (7.5%) had
thrombocytopenia.The majority of neonates had moderate thrombocytopenia 4
neonates (44,4%).Thrombocytopenia was transient and subclinical with no
significant symptoms in all cases.
Conclusions: This study establishes an association of phototherapy with
thrombocytopenia in hyperbilirubinemic neonates, there was a significant
decline in the mean platelet count after phototherapy. There was a significant
correlation found between development of thrombocytopenia and birth weight
.However, thrombocytopenia was transient and there was no bleeding
manifestation.
Key Words: Indirect hyperbilirubinaemia, Neonatal thrombocytopenia.