الفهرس 
Classification of phytochemicalsOnly 14 pages are availabe for public view
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Abstract
The modern pharmacological therapy is costly and associated with multiple side effects resulting in patient non-compliance. Thus, there is a need to explore alternative therapies particularly from nutritional plant sources as these are cost effective and possess minimal side effects. The present stady aimed to determine the effect of phytochemical combinations on liver disorders induced by carbon tetrachloride in rats. The normal rats feeding with basal diet were recorded 19.00, 41.18 and 0.092 for FI, BWG and FER respectively. The injected rats with CCl4 (control positive) showed significantly (P ≤ 0.05) decreased in FI, BWG and FER compared to normal rats by the ratio of -25.51, -38.98 and -21.11%, respectively. On the other side there were significantly (P ≤ 0.05) increased in FI, BWG and FER by the all tested formulae. Treatment of rats with CCl4 caused a significantly (P ≤ 0.05) increased in AST, ALT and ALP by the percent of change 71.45, 22.77 and 155.77%, respectively compared to normal control. On the other side there were significantly (P ≤ 0.05) increased in AST, ALT and ALP by the all tested formulae. The increasing rate was raised with the increasing of the tested formulae feeding levels. Furthermore, feeding of the tested formulae exhibited significant (P ≤ 0.05) improvements in total bilirubin, serum lipid profile, lipoprotein cholesterol fractions and serum glucose of rats induced by CCl4. In conclusion the present study has demonstrated the potency of the selected formulae to partially ameliorate liver disorders in rats induced by CCl4. Also, the tested formulae could be used successfully as a promising tool in the prevention of atherosclerosis by inhibiting LDL oxidation which merits further intensive studies.