الفهرس | Only 14 pages are availabe for public view |
Abstract This was a prospective comparative study conducted on 80 patients with acute pancreatitis (AP); to evaluate and demonstrate role of Interleukin 6 (IL-6), Interleukin 8 (IL-8) and Beta-2 Microglobulin (B2M) in assessment severity of pancreatitis. Comparative study between the 2 groups revealed: Non-significant difference as regards age, gender, BMI and etiology of AP (p > 0.05). Highly significant increase in TLC in SAP group; compared to MAP group; with highly significant statistical difference (p < 0.01). Highly significant decrease in serum albumin in SAP group; compared to MAP group; with highly significant statistical difference (p = 0.0001). Highly significant increase in baseline IL-6, IL-8 and B2-microglobulin, in SAP group; compared to MAP group; with highly significant statistical difference (p < 0.01 respectively). Significant increase in 3rd day IL-6, IL-8 and B2-microglobulin, in SAP group; compared to MAP group; with highly significant statistical difference (p < 0.01 respectively). Highly significant increase in complications and mortality rate, in SAP group; compared to MAP group; with highly significant statistical difference (p < 0.01 respectively). After applying (Forward method) and entering some predictor variables; the decrease in serum albumin; had an independent effect on increasing the probability of SAP occurrence; with significant statistical difference (p = 0.0086, OR = 0.0003). After applying (Forward method) and entering some predictor variables; the increase in serum IL-6; had an independent effect on increasing the probability of SAP occurrence; with significant statistical difference (p = 0.0019, OR = 1.22). |