الفهرس 
Anatomy and physiology of the kidneyOnly 14 pages are availabe for public view
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Abstract
largely due to the lack of a consensus definition in published studies. The incidence of AKI in children admitted to pediatric intensive care units is about 5 percent also in children undergoing cardiac surgery for congenital heart diseases showed incidence between 30 to 40 percent and in children receiving bone marrow transplantation the incidence ranges from 15 to 34 percent.
To establish a uniform definition AKI, the acute dialysis quality initiative formulated the RIFLE classification. RIFLE defines three grades of increasing severity of AKI; risk (class R), injury (class I) and failure (class F) and two outcome classes; loss (class L) and end-stage kidney disease (class E). Therefore, the aim of this study was to assess AKI by RIFLE criteria in pediatric ICU of Menoufia University hospital.
This study was conducted on 120 patients which classified into four groups, Non-AKI group (76 cases) and AKI group (44 cases) which included 12 patient had risk (class R), 20 patients had injury (class I), and 12 patients had failure (class F). all patients admitted to pediatric intensive care unit of Menoufia University from July 2014 to December 2018.
Results of the current study could be summarized as follow:
Severity grading of AKI cases according to pRIFLE criteria showed that 12 (10%) patients were in “R” category, 20 (16.67%) in “I” category, and 12 (10%) in “F” category, respectively. While, 76(63.33% patients were negative.
There were no statistically significant differences between the studied groups regarding sex, age, body weight/kg, height/cm (P=0.59). While body mass index was a significantly increased among failure patients than other groups.
There were statistically highly significant differences between the studied groups regarding system affected, ventilation, complications and fate (P<0.001).
There were no statistically significant differences between the studied groups regarding WBC and hemoglobin. While, failure (class F) had significantly lower platelet than other classes.
Albumin level was significantly lower among injury (class I) and failure (class F) than negative and risk (class R).
There were statistically highly significant differences between the studied groups regarding Elevated creatinine, Elevated BUN, U.O. P, Diminished creatinine clearance, +ve CRP, and +ve nephrotoxic drugs.
Injury (class I) and failure (class F) had significantly higher hospital stay in days, score, mortality risk and PIM than negative and risk (class R).
There were statistically significant differences between live and died participants regarding age, score, mortality risk, PIM, WBC, albumin level, system