الفهرس 
Anatomy of Urinary BladderOnly 14 pages are availabe for public view
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Abstract
Purpose:The aim of this work is to ellucidate the role of diffusion-weighted imaging in T-stage of bladder cancer, to find
correlation between the apparent diffusion coefficient (ADC) and histologic grade and to detect early tumor
recurrence.Materials and Methods: In this retrospective study, 34 patients were gathered, 28 men and 6 women, with ages
ranging from 46 to 90 years, presented with gross hematuria or suspected of urinary bladder tumors detected on U/S
and/or CT examinations. The patients were referred to Radiology department at national cancer institute for MRI
examination after fulfilling inclusion and exclusion criteria. The urinary bladder tumors were classified in accordance with
TNM classification from the American Joint Committee on Cancer into: T1 or lower, T2 (T2a or T2b), T3 (T3a or T3b), and
T4.The mean ADC value of patients with low grade tumor (G1) and patients with high grade tumor (G2 or G3) was done
The results were compared with histo-pathological examination obtained by transurethral resection (TUR) or after radical
cystectomy. Results: The overall accuracy of T stage diagnosis was 74.29% for T2-weighted images, 88.57 % for DW images,
80 % for contrast-enhanced images, and about 88.57 % for T2 plus DWIs. The mean ADC of G3 tumors was significantly
lower than that of G1 and G2 tumors. Conclusion: Our results suggest that adding DWIs to T2WIs lead to marked
improvement regarding the accuracy for differentiating T2 or lower tumors from T3 and higher tumors, helping to limit the
usage of contrast enhanced MRI imaging as a noninvasive diagnostic tool.