الفهرس 
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Abstract
The prevalence of CFMS in EL-Minia University in two years (2017_2018/2019) was 12.5% with total number of cases 2091.the total prevalence as regard to the total ANC cases attached to the university hospital was 0.65%.
The possible risk factors in fetal anomalies in this study were parenteral consanguinity, perinatal maternal infection or administration of drugs, as well as perinatal animal breeding.
the most common affected system is the central nervous system with percentage 32.7% followed by the renal system 18.6% followed with the cardiovascular system 14.8% followed by the chest 8% followed by the musculoskeletal system 7.2% followed by hydrops foetalis 6.5% followed by GIT 5.7% followed by neck 5.3% followed by face which is the least prevalent anomalies with percentage 1.1%.
Hydrops foetalis was the commonest multiple anomalies followed by the lung hypoplasia .
The advanced maternal age had a strong association with increasing the prevalence of CFMS.
Consanguinity had a strong association with increasing the prevalence of CFMS.
Gender of baby had no impact on CFMS prevalence
Mode of delivery had no impact on CFMS prevalence
The outcome of conception no impact on CFMS prevalence
We recommend attaching another detailed studies with perfectly linked with MRI to enhance the CFMS detection.