الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Ovarian cancer is among the most common female genital tract cancers and has the worst prognosis. This is largely caused by the fact that these cancers are detected at late stage of the disease.
Ovarian cancer is the most common cause of death among women with gynecologic malignancies. More than half of women with ovarian cancer present with advanced stage disease (FIGO III/IV) at time of presentation.
Surface epithelial-stromal tumor is the most common type of ovarian malignancy (more than 90%). Also there are other three types which are sex cord stromal tumor, germ cell tumor (teratomas) and mixed tumors.
Spread of the disease is often by local extension, by intra-abdominal dissemination to other sites within the peritoneal cavity, and by lymphatic spread to pelvic and para-aortic nodes in the retro peritoneum.
Ovarian cancer at its early stages (I/II) is difficult to be diagnosed but in advanced stages it can be diagnosed by blood test called CA125, pelvic examination and imaging methods including CT scan and ultrasound.
Current best practice includes primary surgery by gynecological oncologist for diagnosis, staging, and cytoreduction, followed by chemotherapy.
Surgical treatment may be sufficient for malignant tumors that are well-differentiated and confined to the ovary. Addition of chemotherapy may be required for more aggressive tumors.
The currently accepted management of advanced stage ovarian cancer is a primary debulking surgery (PDS) in order to achieve an optimal cytoreduction (defined as residual tumors less than 1 cm) followed by chemotherapy up to 6 cycles.
However, cytoreductive surgery is associated with high mortality and morbidity rates, with misleading results on survival. Such results suggest that this surgical strategy should be reconsidered, particularly in patients with massive intra-abdominal spread.
Several cycles of chemotherapy are generally given after primary surgery. Secondary surgery performed after a few cycles of chemotherapy before further cycles of chemotherapy, is called interval debulking surgery (IDS).
The aim of this study was to analysis of ovarian mass cases presented in Alexandria university gyne oncology high specialized center as regard; percentage among different cancer cases, age distribution, clinico pathological aspect, histopathology, stage at presentation, grade at presentation, CA125, primary modality of therapy. Outlining the magnitude of the problem in order to help in designing a program for prevention, and Building up a data base for future reporting of new cases.
This study was carried out on all cases with ovarian mass at Alexandria university gyneoncology highly specialized center from June 2016 to June 2018.