الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Uterine leiomyomas are the most common pelvic tumors of women. Lifetime incidence among Caucasian women is 40 % by age 35 and more than 70 % by age 50.
Uterine leiomyomas are associated with symptoms such as abnormal bleeding, pain, pressure, urinary symptoms, or infertility. They affect women primarily during their reproductive years and decrease in size after menopause.
This risk of hemorrhage leads not only to an increased transfusion rate but also to the need for hysterectomy and other potential operative complications. Numerous medical and surgical techniques have been developed to minimize potentially significant blood loss during abdominal, laparoscopic, and robotic-assisted myomectomies.
This study was a randomized control study conducted on 40 females with myomas and undergoing surgical myomectomy. Patients are divided into two groups high dose group; 20 cases received (500 μg epinephrine), and low dose group ; 20 cases received (250 μg epinephrine).
The results of the comparison between the two studied groups regarding the operative time, and the amount of blood loss were not significant (P>0.05), but it was statistically significant regarding the change in blood pressure (P=0.01).
According to the change in Hemoglobin level pre and postoperative, there was no statistical difference between both groups pre and postoperatively (P=0.935, 0.640 respectively).
Results of the change in heart rate pre & post-injection showed that there was a statistical difference between both groups regarding postinjection HR(P=0.018).
Although the rate of intraoperative complications of premature ventricular contraction was high in the high dose group compared to the low dose group ,but the difference did not reach any statistical significance.
Transient, non-serious but significant increases in systolic and diastolic blood pressure and heart rate following intramyometrial epinephrine injection occurred in 20% of cases in the low dose group and 60% of cases in the high dose group showing a significant difference (p=0.010