الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Objective: To report data on the feasibility, safety, and
effectiveness of activated platelet rich plasma in accelerating
the healing rate of non-ischemic DFU.
Design: This is a prospective, randomized, controlled,
blinded study that will be conducted in Ain Shams university
and Sheikh Zayed Specialized hospital vascular surgery unit.
Methods: 30 patients with non-ischemic DFU were
classified into two groups: group A: Patients with nonischemic
DFU and were treated with a novel modality i.e.: PRP
injection in the healing edge and the floor of the targeted ulcer.
group B: Patients with non-ischemic DFU who had usual
standard care i.e.: moist dressing with or without collagenase
ointment. All cases had a minimal debridement prior to
treatment, Here in our study the demographic data i.e. Age, sex,
medical history were homogenously distributed among both
groups. All cases in both groups were non ischemic after
successful revascularization either by OR or ER.
Results: The rate of complete healing for ulcers in group A was
achieved in six patients (40%) at the fifth week, while
five patients (33.33%) were healed completely by the
sixth week and only one patient (6.67%) healed in the ninth week. 26.67 % (n=4 cases) in group B showed
complete healing rate by eighth week and 40% (n=6
cases) were healed by ninth week while 33.33% (n=5
cases) were healed in the tenth week. P value was
statistically significant <0.001 between the groups.
Conclusion: Activated platelet rich plasma is a novel modality
in treatment of diabetic foot ulcers which is
feasible, save and effective with high rate of limb
salvage rate and clinical improvement.