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العنوان
The use of Nano graft combined with leukocyte-platelet rich fibrin in ridge preservation
(A Randomized controlled Clinical and Histological study)
Thesis submitted in partial fulfillment of the requirements of
The master degree of periodontology
المؤلف
Sayed ,Mazen Mostafa
هيئة الاعداد
مشرف / مازن مصطفي سيد
مشرف / أحمد يوسف جمال
مشرف / وليد محمد عباس
تاريخ النشر
2020
عدد الصفحات
IIIXV;180P.:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأسنان
تاريخ الإجازة
16/8/2020
مكان الإجازة
جامعة عين شمس - كلية طب الأسنان - علاج لثه
الفهرس
Only 14 pages are availabe for public view

from 200

from 200

Abstract

In the current times, where implant placement is the most favored option for replacement of a missing tooth, preservation of alveolar ridge is of vital importance. Following tooth extraction, dimensional changes of the residual alveolar ridge are inevitable. Thus, to maintain the bone volume, placement of various graft materials inside freshly extracted socket is advocated by multiple studies as a ”ridge preservation technique.”
The aim of the present study was to evaluate three months post-extraction augmented ridge using either nanocrystalline hydroxyapatite (Nano graft) combined with L-PRF or L-PRF as a sole grafting material compared to natural healing without any grafting materials (control). This comparison was done histologically, clinically and radiographically.
Clinical parameters included; vertical bone height and bone width that were recorded at baseline and at three months after extraction. Moreover, histomorphometric parameters included; area fraction of osteoid bone three months after extraction by histomorphometric analysis. Radiographic parameters included baseline CBCT and another one done three months after extraction with subsequent measurement of bone height and bone width.
A core biopsy was taken three months after tooth extraction which has undergone histomorphometric analysis; implant placement was also done at the same time.
By histomorphometric analysis a higher mean surface area of newly formed bone was detected in L-PRF group than Nano graft combined with L-PRF group than control group with a significant difference between all groups.
Clinically in the present study, it was found that bone height decreased with a higher percent in (control group) than (Nano graft combined with L-PRF group and L-PRF group) with a significant difference between control group and other two groups while there was no significant difference between Nano graft combined with L-PRF group and L-PRF group.
In addition, this study showed that bone width decreased least in Nano graft combined with L-PRF group than L-PRF group than control group with a significant difference between all groups.
Radiographically, CBCT revealed that bone hight decreased with higher percent in (control group) than ( Nano graft combined with L-PRF group and L-PRF group) with a significant difference between control group and other two groups while there was no significant difference between Nano graft combined with L-PRF group and L-PRF group.
Accordingly bone width decreased least in (Nano graft combined with L-PRF group) than (L-PRF group) than (control group) with a significant difference between all groups.