الفهرس 
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Abstract
Antistreptolysin O (ASO) titre is a blood test to measure antibodies against strepolysin O, a substance produced by group A Streptococcus bacteria.
ASO particularly useful for the diagnosis of acute rheumatic fever and acute post streptococcal glomerulonephritis. Acute rheumatic fever is an autoimmune disease that follows infection with group A Streptococci (GAS); however, the isolation of GAS is uncommon (< 15%), so confirmation of the diagnosis often relies on streptococcal antibody tests.
Streptococcal titers vary according to a number of factors, including age and population. In developed countries, where impetigo caused by GAS is uncommon, streptococcal titers in the population primarily reflect the incidence of pharyngeal infection with GAS; therefore, the titers in healthy people are low in early childhood, rise to a peak in children aged 5 to 15 years, decrease in late adolescence and early adulthood, and hen flatten off after that.
The ASO titre tends to rise a week following infection, peaks at 3 to 5 weeks, and begins to decline after 8 weeks; and it responds more vigorously to pharyngeal infection than skin infection. The Anti-DNase B (ADB) titre peaks at 6 to 8 weeks after infection and begins to decline at 12 weeks, and it responds vigorously to both pharyngeal and skin infections. Therefore, subjects with recent pharyngitis or skin infections should not be included in the sample. .
The aim of this study was to determine upper limit of normal range of anti streptolysin O titre in normal school children from 6-15 years old in Qaliobia Governorate.