الفهرس 
Severe sepsis and septic shockOnly 14 pages are availabe for public view
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Abstract
Sepsis, including severe sepsis and septic shock, remains a major cause of morbidity and mortality worldwide [1]. The mortality rate of severe sepsis is 20–30%, accounting for about 30–50% of hospital deaths[2]. Even though the mortality rate of severe sepsis has decreased markedly since the introduction of early resuscitative treatments, including early goal-directed therapy (EGDT) survivors of sepsis are at increased risk of death, months and even years after hospital discharge [1]. Biomarkers can be used as independent prognostic factors to evaluate the outcome of patients with severe sepsis or septic shock.This prospective cohort study was conducted on one hundred Egyptian individuals divided into two groups; the control group comprised fifty clinically free, age matched healthy individuals and the study group enrolled fifty critically ill patients with severe sepsis and septic shock diagnosed according to according to the [SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference] [11] admitted to ICU of shebin ekom teaching hospitalThe aim of this study is to Evaluate the ability of lactate/albumin ratio to predict outcome as regards mortality, length of ICU stay and extent of organ dysfunctions in patients with severe sepsis and septic shock.In this study, we found that serum levels of lactate and lactate/albumin ratio were higher in the study group on days 0 and 1 than control group with statistically significant difference (p value<0.001) whereas serum albumin was significantly lower in the study group on days 0 and 1 than the control group with (p value<0.001).