الفهرس 
HYPOTHYROIDISMOnly 14 pages are availabe for public view
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Abstract
Aim of the Work: To study the relation between maternal obesity (indicated by BMI), maternal hypothyroidism, thyroid peroxidase antibodies and anti-thyroglobulin positivity during early pregnancy.
Patients and Methods: The study was conducted in Ain shams University Hospital and National Institute of Diabetes and Endocrinology. The study included women aged 19–40 who were pregnant at the 4th –8th weeks of gestation.
Results: obese group had the highest prevalence of overt (5.33%) and subclinical hypothyroidism (2.6 %), highest mean TSH value, p value (0.007*). And the lowest mean FT4 with p value (0.017*) .Also obesity was associated with the highest prevalence of anti TPO (16%) and anti TG Abs (12%).
Conclusion: we concluded that maternal obesity may be associated with TPO anti TG positivity, subclinical hypothyroidism and overt hypothyroidism. Screening of thyroid function in obese pregnant females can detect maternal hypothyroidism and prevention of its hazard’s effects for both mother and fetus.