الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Preeclampsia(PE) is a hypertensive disorder unique to pregnancy and responsible for up to 25% of maternal deaths. Preeclampsia classified according to time of onset as Early Onset Preeclampsia where preeclampsia occurs at 34 weeks gestational age and Late Onset Preeclampsia occurring at >34 weeks of gestation. Criteria for a diagnosis of preeclampsia: hypertension of at least 140/90 mmHg on two separate occasions 4 hours apart accompanied by significant proteinuria of at least 0.3 g in a 24-hour collection of urine arising de novo after the 20th week of gestation in a previously normotensive woman and resolving completely by the 6th postpartum week. We aimed to evaluate role of platelet count and platelet indices (MPV, PDW) in prediction of late onset preeclampsia and its severity. This study included 200 normotensive pregnant women with risk factor of preeclampsia. After informed consent, Full history taking, general and abdominal examination, abdominal ultrasonography and laboratory investigations (for platelet count, platelet indices and urineanalysis). Platelet indices including Platelet count, MPV and PDW were measured first between 28 and 32 week gestation and between 34 week gestation& delivery. Statistical analysis of our findings revealed the following: There were significant differences between studied groups regarding platelet count, MPV and PDW between 28 and 32 week gestation where Platelet count decreased, MPV and PDW increased in preeclampsia. These changes are more pronounced between 34 week gestation& delivery in severe preeclampsia when compared to mild preeclampsia. The study concluded the role of platelet count and platelet indices in predicting pre-eclampsia and its severity The study recommended Platelet count and platelet indices as biomarkers for prediction of pre-eclampsia and to differentiate between mild and severe PE.