الفهرس 
INDUCTION OF LABOROnly 14 pages are availabe for public view
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Abstract
This randomized double blind controlled study was aimed
to compare the efficacy of the use of foley‘s catheter with
either misoprostol or placebo to improve induction to delivery
interval in pregnant women with unfavorable cervix undergoing
induction of labour on similar number of nullipara (25 case)
and multipara (25 case) to be of total 50 patients in each group.
The primary outcome was induction to delivery interval,
while Secondary outcomes were uterine contractile
abnormalities, mode of delivery, maternal and neonatal outcome,
neonatal birth weight, Apgar score, any maternal or fetal
complication and the amount of oxytocin used for induction
Findings:
No significant difference between the studied groups
regarding demographic characteristics as age, BMI, GA &
bishop score (p=0.238, 0.839, 0.490 &0.460 respectively).
Oxytocin duration and total dose were significantly
lower in combined group (6.6±1.6 & 9.8±4.1 respectively) than
in Foley’s group (8.8±1.6 &12.7.0±4.9 respectively) as p<0.001
&0.033 respectively.
There was Non-significant difference between the
studied groups regarding mode of delivery and indications of
CS (p=0.480& 1.000 respectively). The majority of both group had VD (76.0% &86.0% respectively) and half of cases in
combined group, the CS was indicated due to Fetal distress and
in foley group due to Non-progressive labor.
The labor stages (latent, active, second and total) were
significantly shorter in combined group (5.8±0.5, 6.5±0.3,
26.9±1.6 &12.9±0.9 respectively) than in Foley’s group
(4.9±0.4, 4.4±0.6, 30.8±3.0 & 9.9±1.0) (p<0.001 for all). On
the other hands, no significant difference in third stage (6.3±1.9
versus 7.2±1.6 &p=0.098).
Combined group non-significantly had more frequent
uterine hyperstimulation (20.0% versus 4.0%) and perineal tear
(36.0%versus 16.0%) but less frequent postpartum hemorrhage
(4.0% versus 8.0%) as p=0.189, 0.196 & 1.000 respectively.
No significant difference between the studied groups
regarding fetal and neonatal side effects as Fetal distress, Birth
weight, APGAR1, APGAR5 and NICU admission as p=0.609,
1.000, 0.411, 0.861, 0.768 &1.000 respectively.