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العنوان
Intranasal injection of Botulinum toxin type A in treatment of allergic rhinitis /
المؤلف
Hassan, Alaa Nabil El-Sayed.
هيئة الاعداد
باحث / الاء نبيل السيد حسن سيد
مشرف / بليغ حمدي علي
مشرف / أسامة جلال عبد النبي
الموضوع
Rhinitis. Allergy - Treatment.
عدد الصفحات
125 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الحنجرة
تاريخ الإجازة
1/1/2019
مكان الإجازة
جامعة المنيا - كلية الطب - الأذن و الأنف و الحنجرة
الفهرس
Only 14 pages are availabe for public view

from 139

from 139

Abstract

The aim of this study is to evaluate the result of intra nasal injection of Botox in treatment of allergic rhinitis patients.
Results
This study included 20 patients (aged from 15-52 years old and of both sexes , 12 males and 8 females ) divided into 2 groups :
Group(A), study group (BTA group) : included 10 patients were injected by BTA in inferior , middle turbinates and septum .
Group(B), control group (saline group) : included patients were . injected By saline in inferior , middle turbinates and septum .
No significant associations were found between patients‘ age or sex and the effect of BTA on allergic rhinitis.
In this study patients who injected with BTA in inferior and middle turbinates and septum showed significant improvement in the parameter of rhinorrhea and sneezing while there is no significant change I parameter of nasal obstruction or nasal endoscopy.
Conclusion
Botox type A (BTA) could be a safe and effective treatment of cases with allergic rhinits with persistent symptoms despite of medical treatment, morestudies including more number of patients with long term follow up should be performed,we need protocol for the dose and sites of injection of BTA, Longer duration for evaluation is needed to measure the effet of BTA over time,When we consider that botox injection may be needed every 3-6 months as indicated by some studies, the cost benefit relationship between botox and medical therapy should be evaluated.