الفهرس 
1. IntroductionOnly 14 pages are availabe for public view
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Abstract
The present study were carried out to evaluate the effect of ginger and ginseng roots as semi-modified diet on lipid fractions of hyperlipidemic/ hypercholesterolaemic (obesity) albino rats. These were based on the agents contain biochemical mater, protein and a large amount of phenols which used as lipotropic factors and antioxidant characters. The fat in the human body (obesity) lead to many health problems and disorder physically for many people and cause many diseases (narrow arteries of heart disease - atherosclerosis - diabetes - increased blood pressure...) and found that pharmaceutical pharmacy lead to harmful side effects on the body that study the effects of ginger and ginseng roots to now its effects of hypolipidemia in blood .The studied was carried out as follows.
I- The chemical composition of ginger and ginseng roots
II- An experiment to add these roots on rats feed and show its effect on the lipoprotein and the kidneys and lives function
I- The chemical composition of ginger and ginseng roots
1- Found that ginger roots contain 6.25% protein 14.2% crud lipid, 61.68% carbohydrate, 197.1 mg/100 g. d.w phenols in addition to 116.09 mg/l00 g flavonoids.
2- Ginseng roots contain 7.62 protein, 9.15% crud lipid, 66.91 carbohydrate, 528.69 mg/100g phenols and 311.39g/100g flavonoids.
3- ginger roots contained 17 components of phenol and found that Cateachin, Caffeic acid, Ferulic acid and Rutin were found in high levels.
4- ginseng roots contained 20 components of phenols and found that Ferulic acid, Caffeic acid, P-hydroxybenzoic acid and Cateachin were found in high amounts.
II- The assessment of bio-chemical of ginger and ginseng roots
Rats divided into 6 group.
1- The first group (I) negative control, while the rats of group 2-6 fed on high-fat hyperlipidemic diet to bring about in increase in the proportion of lipids.
2- The second group (II) positive control, continue feeding on hyperlipidemic diet.
3- The group (III and IV) have been added 5% and 10% ginger roots to a hyperlipidemic diet respectively.
4- The group (V and VI) have been added 5% and 10% ginseng roots to a hyperlipidemic diet respectively.
5- Take the blood samples after 15 and 30 days at the end of the experiments.
6- After the end of the experiments killed rats to assess the internal organs weight (liver – kidneys - heart) and summarized results obtained as follows:
The results of higher fat nutrition leading to hyperlipidemic diet indicated a significant increase in levels of total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL-c) and very low density lipoprotein (vLDL-c) While showing high-density lipoprotein (HDL-c) a decrease in level and result in the use of ginger and ginseng roots to reduce the advance impact of hyperlipidemic diet. In addition, lead to improved levels of both cholesterol and triglycerides and low-density lipoprotein.
1- Stimulation hyperlipidemic diet liver enzymes AST ,ALT and ALP activity was observed and results in the use of ginger and ginseng roots to reduce the harmful effects of hyperlipidemia and led to improved activity of liver enzymes.
2- Hyperlipidemic diet lead to decrease in total protein and also albumin and globulin, while the roots of ginger and ginseng lead to increase the total protein and albumin comparing with positive control.
3- Feeding on hyperlipidemic diet leading to significant in the activity of GGT enzyme, and also increase in amount of total and direct bilirubin, while adding roots of ginger and ginseng improved this stages.
4- Hyperlipidemic diet lead to significant increase in the levels of Urea, Creatinine and Uric acid in blood compared with negative control. Moreover adding the ginger and ginseng roots to infected rats hyperlipidemic diet leading to decrease Urea level and improve the level of Creatinine and Uric acid.
5- The use of ginger and ginseng roots to decrease in the blood glucose levels of infected rats with hyperlipidemia.
6- Hyperlipidemic diet leading to decrease the RBCs, Hemoglobin ,WBCs, and Platelets counts comparing with the normal group. Also adding the roots of ginger and ginseng leading to an increase the amount of the above blood fraction comparing with positive control.
7- The feeding on hyperlipidemic diet showed an increase in oxidative enzymes SOD and CAT activity as well as MDA, and adding roots of ginger and ginseng showed a decrease in the activity of the enzymes comparing with positive control.
8- Rats fed on hyperlipidemic diet showed a significant increase in the body weights. As well as the weights of the liver, kidney, and hearts as compared to healthy reference and resulted in the use of ginger and ginseng roots to improve the weights of rats and lead to reduced weight gain and improve organs weight compared with rats infected with hyperlipidemia.