الفهرس 
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Abstract
The aim of this study is to evaluate the levels of betatrophin in children with T1DM , and to study their correlations with different parameters
Our study included three groups ; group I: 30 child newly diagnosed with T1D (within one year ) , group II: 30 child with long standing T1D (diagnosed for more than five year ) and group III : 30 child apparently healthy, age and sex matched to the diabetic children as a control group .
In our study, we found that the diabetic groups had significantly higher levels of fasting and postprandial plasma glucose, HbA1c % , T.cholesterol , LDL and TG and a significantly lower levels of fasting C-peptide than the control group .On the other hand , we found that the long standing T1D children had higher levels of lipid profile (TC,LDL,TG) ,ACR and lower level of LDL than the newly diagnosed and the control groups.
Also , we found that the diabetic groups had higher levels of betatrophin than the control where and the newly diagnosed diabetic children had a significantly higher level of betatrophin than long standing diabetics and the control groups .
Finally , the betatrophin had a significant positive moderate correlations with HA1C and TG levels in group I and a significant strong positive correlation with HbA1c levels in group II.