الفهرس 
Aim of the workOnly 14 pages are availabe for public view
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Abstract
Assessment of diastolic function should be an integral part of
evaluation of cardiac function because 50% of patients with heart failure
have preserved LVEF. Currently, Echocardiography is the best noninvasive
way to evaluate diastolic function and to estimate filling
pressures. M-mode, 2-D and Doppler echocardiography are all helpful in
evaluating diastolic function according to ASE and EAE guidelines.
Preclinical alterations of LV systolic function have been
demonstrated in patients with diastolic dysfunction with normal EF.
Hence, early detection of such preclinical LV changes represents a
clinical finding that would justify aggressive treatment aiming at reducing
cardiovascular risk. However, the main cause of diastolic dysfunction is
arterial hypertension; conventional echocardiography detects
abnormalities in LV systolic function in advanced stages of hypertensive
heart disease, when a clear LV remodeling/hypertrophy is evident.
TDI is a new technique that enables assessment of regional
myocardial deformation by assessment of strain and strain rate. In
contrast to TDI, 2D STE is angle-independent technique that may allow
an accurate assessment of segmental myocardial deformation.
This study was designed to evaluate LV systolic function in
patients with diastolic dysfunction using 2D STE based longitudinal,
circumferential, radial strain and strain rate in those patients.
95 individuals were enrolled, divided into two groups: group I
(patients group) 70 patients with criteria of diastolic dysfunction and
group II (control group) 25 young age (25-35) years old, healthy, age and
sex matched volunteers.
Assessment of diastolic function should be an integral part of
evaluation of cardiac function because 50% of patients with heart failure
have preserved LVEF. Currently, Echocardiography is the best noninvasive
way to evaluate diastolic function and to estimate filling
pressures. M-mode, 2-D and Doppler echocardiography are all helpful in
evaluating diastolic function according to ASE and EAE guidelines.
Preclinical alterations of LV systolic function have been
demonstrated in patients with diastolic dysfunction with normal EF.
Hence, early detection of such preclinical LV changes represents a
clinical finding that would justify aggressive treatment aiming at reducing
cardiovascular risk. However, the main cause of diastolic dysfunction is
arterial hypertension; conventional echocardiography detects
abnormalities in LV systolic function in advanced stages of hypertensive
heart disease, when a clear LV remodeling/hypertrophy is evident.
TDI is a new technique that enables assessment of regional
myocardial deformation by assessment of strain and strain rate. In
contrast to TDI, 2D STE is angle-independent technique that may allow
an accurate assessment of segmental myocardial deformation.
This study was designed to evaluate LV systolic function in
patients with diastolic dysfunction using 2D STE based longitudinal,
circumferential, radial strain and strain rate in those patients.
95 individuals were enrolled, divided into two groups: group I
(patients group) 70 patients with criteria of diastolic dysfunction and
group II (control group) 25 young age (25-35) years old, healthy, age and
sex matched volunteers.
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