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العنوان
The relation between Helicobacter pylori infection in Women and unexplained infertility /
المؤلف
Nafie, Mahmoud Abdel Samie.
هيئة الاعداد
باحث / محمود عبد السميع نافع
مشرف / حامد السيد اللقوه
مشرف / زكريا فؤاد سند
مشرف / محمد السباعي عنتر
مناقش / حامد السيد اللقوه
الموضوع
Obstetrics. Gynecology. Helicobacter pylori infection- Women. Infertility.
تاريخ النشر
2019.
عدد الصفحات
100 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض النساء والتوليد
تاريخ الإجازة
6/10/2019
مكان الإجازة
جامعة المنوفية - كلية الطب - أمراض النساء والتوليد
الفهرس
Only 14 pages are availabe for public view

from 99

from 99

Abstract

Unexplained infertility represents a significant clinical problem, the
evaluation and management of which leave a lot to be desired. The lack of
universally accepted diagnostic criteria makes it difficult to study this problem
because of the heterogeneity in the samples selected for study. Agreement on
the definitions is a first step in this process of creating homogeneous groups
for study.
The Practice Committee of the American Society for Reproductive Medicine
(ASRM) has published guidelines for a standard infertility evaluation. It includes
semen analysis, assessment of ovulation, hystero-salpingiogram, and/or
laparoscopy, when the results of a standard infertility evaluation are normal,
practitioners assign a diagnosis of unexplained infertility. Unexplained infertility
account is approximately 15% to30%.
H.pylori is a Gram-negative bacterium responsible for the large majority of
chronic gastritis, peptic ulcers and mucosal-associated lymphoid tissue
(MALT) lymphoma.
The pathogenicity of H.pylori infection depend on the inflammatory
response to chronic infection, including the strain-specific factors, the host’s
immune response, and environmental factors.
By the end of this study, data of 60 participants (30women in group 1 and
30 women in group 2) were statistical analyzed:
The mean age of included women was 26.26 in cases group and 27.65 in
control group.
Regarding type of infertility in the study group 7 were complaining of
secondary infertility (23.3%), and 23 women were complaining of primary
infertility (76.7%).The mean of the duration of infertility in case group is 2.54.
There was a significantly higher proportion of women with positive serum
H.pylori antibodies among women with unexplained infertility 19 (63.3%),
when compared to control women 10 (33.3%).
There was a significantly higher proportion of women with positive cervical
mucus H.pylori antibodies among women with unexplained infertility 16
(53.3%), when compared to control women 7 (23.3%).
There was non significantly higher proportion of women with positive
serum H.pylori antibodies among women with primary infertility 10 (43.5%),
when compared to women with secondary infertility 4 (57.1%).
There was non significantly higher proportion of women with positive
cervical mucus H.pylori antibodies among women with primary infertility 5
(21.7%) when compared to women with secondary infertility 2 (28.6%).
In Conclusion, in women with unexplained infertility, H.pylori IgG
antibody in the serum and the cervical mucus was significantly prevalent
compared with that in fertile women.