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Abstract Radiofrequency ablation of osteoid osteoma is a highly effective, efficient, minimally invasive and safe treating modality. Many scientific peer-reviewed literatures support the osteoid osteoma treatment with radiofrequency ablation (RFA). RFA provides outcomes comparable and competitive to those of surgical excision in the terms of destruction of the tumor nidus and relief of symptoms in almost all patients. Due to the difficulty locating the nidus intra-operatively, surgical treatment may result in weakening of the remaining bone, requiring grafting or internal fixation. These complications are avoided with RFA. Results of the peer-reviewed literature support the use of RFA for the treatment of osteoid osteoma. Surgery remains the standard treatment in cases where histology of the lesion is in doubt, neurovascular structures are within 1.5 cm or in repeated failure of any other minimally invasive ablative technique or percutaneous resection. |