الفهرس 
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Abstract
The aim of the present study was to investigate the antioxidant function of aloe vera gel, olive pomace, vitamin C, and vitamin E as a feed additive on gastro-intestinal functionality and integrity of growing rabbits.The study was carried on 48 New Zealand White rabbits (NZW) of 6 week old. The experiment lasted for 10 weeks. Rabbits were equally divided into 8 groups, (control) group which fed a basal diet, (A) group fed on a basal diet and water supplemented with Aloe vera gel at a dose (500mg/L), (C) group fed a basal diet and water supplemented with vitamin C(1g/4L), (E) group fed a basal diet and water supplemented with vitamin E (1ml/L), (O) group fed a basal diet to which 10% olive pomace was added, (CE) group fed a basal diet and water supplemented with both vitamins (C&E) by the previous doses, (ACE) group, its water supplemented with aloe vera gel ,vitamin C and vitamin E by the previous doses, (OCE) group fed the diet to which olive pomace and both vitamins in water with the previous doses was added. Performance parameters were measured live body weight (LBW), feed intake (FI) and feed conversion ratio (FCR) at the end of the experiment. Serum samples were collected to measure biochemical and antioxidant parameters. Tissue samples of duodenum were collected and prepared for histomorphological and molecular studies. The results revealed that: [1] Most supplements had no significant effect on body weight, while (FI) was decreased in (C), (O) and (OCE) groups. Moreover, the feed conversion ratio FCR was only decreased in group (C). [2] A hypoglycemic and a hypocholesterolemia effect was detected in group (A), (E), (CE), (ACE) and (OCE). [3] There were no significant variations in liver enzymes (ALT and AST) and kidney function tests (Creatinine and Urea) between all groups. [4] Regarding the antioxidant parameters of all supplemented groups, a significant increase of most of antioxidant parameters was determined with a significant decrease of serum Malonaldehyde (MDA).[5] DNA concentration in duodenum and pancreatic tissues increased significantly in group supplemented with (ACE), while protein concentration of pancreatic tissue recorded a significant higher value in group (CE), DNA to Protein ratio recorded a significant increase in groups supplemented with (A), (C) and (ACE).[6] The duodenum morphometry showed best villous height to crypt depth ratio in group supplemented with (A) than other supplemented groups. Conclusively it was obvious that the rabbits supplemented with aloe vera gel mixed with vitamin C and E in supplied water had the best antioxidant activity and the used supplements have no harmful effect on liver and kidney measured parameters. In addition the olive pomace supplemented diet can be considered as a cheapest diet.