الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Diabetic patients with normal left ventricular ejection fraction (LVEF) are frequently associated with asymptomatic left ventricle systolic dysfunction, that LVEF is not known to be a sensitive marker for the early detection of subclinical LV systolic dysfunction
Objectives: The aim of this study is to use a new echocardiographic technique (Speckle tracking echocardiography) for early detection of left Ventricle systolic Dysfunction in diabetic and pre diabetic patients
Methods: The study included Seventy patients and thirty five age matched healthy persons as a control group Patients group included 35 diabetic (17 males -18 females) and 35 pre diabetic (15 males -20 females).They were subjected to clinical assessment ,12-Leads Resting Electrocardiogram, Laboratory Investigation: Fasting plasma glucose,2-h plasma glucose, Hb A1c ,Serum Creatinine to estimate creatinine clearance rate, Urine Albumin ⁄ Creatinine rate
Trans-thoracic Echocardiography and 2 D Speckle Tracking Echocardiography
Results: Regarding global longitudinal strain (GLS) measured by speckle tracking echocardiography, results revealed that GLS was significantly lower in diabetic patients when compared to pre diabetic and control groups . Also, GLS was significantly lower in pre diabetic group when compared with control group
Conclusion: The results of this study showed that normotensive non ischemic diabetic and pre diabetic subjects with normal LVEF have evidence of impaired left ventricular systolic function compared to control subjects.