الفهرس 
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Abstract
In this study the clinical responses and quality of life changes after plasma exchange in patients with moderate to severe degree of myasthenia gravis, we found that:
The age of the patients was significantly correlated the improvement in QMG and QOL scores as younger patients had better outcome after plasmapheresis.
There were no significant changes in QMG and QOL scores after plasmapheresis regarding patient’s gender.
The patients with shorter duration of the disease have significant improvement in QMG score and high significant improvement in QOL score after plasmapheresis.
The presence of AchR Antibodies had a high significant improvement in QMG scores after plasmapheresis and lesser significant improvement in QOL scores.
The elevation of the AchR Antibodies titer is highly correlated with the improvement in QMG score and to lesser extend to QOL score improvement.
Thymectomy showed significant improvement in QMG in patients after plasmapheresis compared with non thymectomy patients. But with no significant changes after plasmapheresis in QOL scores in both thymectomy and non thymectomy patients.
Regarding thymus gland pathology, we found thymic hyperplasia had a better improvement in QMG and QOL scores after plasmapheresis, than thymoma.
Regarding other autoimmune disorders ,there were no significant changes in initial QMG scores or percentage of changes in QMG scores after plasmapheresis between patients with thyrotoxicosis or systemic lupus and patients with no other autoimmune disorders, with mild decrease in initial QOL score in systemic lupus