الفهرس | Only 14 pages are availabe for public view |
Abstract Anemia is a public health problem that affects both developed and developing countries. It can occur at all stages of life, and is most prevalent in high-risk individuals, such as pregnant women and children between the ages of 2 and 12 years. Around 50% of all cases of anemia worldwide are thought to be caused by iron deficiency. The main risk factors for iron deficiency anemia are low iron intake, different levels of chronic blood loss, and malabsorption. Iron-deficiency anemia (IDA) is the most common type of malnutrition in the world, and is also the main cause of anemia in children. It has been reported that IDA may cause variable platelet dysfunction and this can be reversed by iron therapy and although it is thought that iron containing enzymes of the platelets might have a role, the main cause of this abnormality is not clear. The present study was designed to investigate platelet aggregation in children with iron deficiency anemia. It included 50 children proved as iron deficiency anemia and another 50 healthy, non-anemic children as a control group. All were underwent full history taking, clinical examination and laboratory investigations with stress on hemoglobin levels, serum iron, ferritin, total iron binding capacity and ADP- platelet aggregation. |