الفهرس 
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Abstract
Summary
HCC is the most common type of tumors that can develop as a
primary cancer of the liver. Most cases of HCC are secondary to
either a viral hepatitis infection (hepatitis B or C) or cirrhosis.
In Egypt, hospital-based studies have reported an overall
increase in the relative frequency of all liver-related cancers in Egypt
(>95% as HCC) with increasing importance of HCV infection in the
etiology of liver cancer, with declining influence of HBV and
HBV/HCV co-infection.
Early detection of HCC is mandatory for early intervention to
resect or ablate the lesion which has better prognosis but require
smaller tumor and good general condition.
Mean platelet volume (MPV) is a parameter of routine blood
count that provides an insight into platelet function and activation.
Changes of MPV have been actively investigated in many liver
diseases such as steatosis, cirrhosis, hepatitis and HCC.
In the recent decades many tumor markers have been
investigated and proposed but the lack of efficient and precise HCC
biomarkers prevents early detection resulting in a poor prognosis.
Recently, mean platelet volume (MPV) and MPV/platelet count (PC)
ratio have been proposed as potential markers of HCC.
This study was carried out to verify MPV and MPV/PC ratio in
diagnosis of HCC in Egyptian patients with chronic hepatitis C
related liver cirrhosis.