الفهرس | Only 14 pages are availabe for public view |
Abstract Summary and Conclusion Attention deficit hyperactivity disorder (ADHD) is the most common neurobehavioral disorders of childhood, and one of the most prevalent chronic diseases found in school children, ADHD is characterized by persistent hyperactivity, impulsivity and inattention that impairs educational achievement and/or social functioning. Inattention, hyperactivity and impulsivity are behavior characteristics present in all young children which gradually decrease as they mature into adulthood. However, children with ADHD are distinguished from their normal peers by increased inattention, hyperactivity and impulsivity relative to that expected for their age and gender and these differences in behavior often continue to adulthood. Iron is an indispensable element in biological systems and is responsible for the function of many prosthetic groups, including oxygen transport, DNA synthesis, electron transport, and cellular proliferation and differentiation. Several studies have suggested that iron deficiency may be related to the pathophysiology of attention deficit hyperactivity disorder (ADHD) due to the role of iron in the production of dopamine and noradrenaline. The aim of our study was to determine the serum level of iron and transferrin saturation as a markers of iron status in ADHD children. |