الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
This prospective study was conducted on 50 adult patients who attended ERCP Unit of Benha University Hospitals & international medical center (IMC) with biliary obstruction during the period from November 2016 to April 2018, it was aimed to study the diagnostic value of carcinoembryonic antigen (CEA), carbohydrate antigen19-9 (CA19-9), carbohydrate antigen 125 (CA125) in serum and in bile by ERCP for discrimination between benign and malignant pancreatobiliary diseases.This study included two groups: the first one included 25 patients with benign biliary obstruction and the second included 25 patients with malignant biliary obstruction.All patients were above 18 years, had definite diagnosis of benign or malignant obstruction using imaging techniques, laboratory tests and ERCP were included in this study.All patients with previous ERCP and stent placement, active hepatic disease, presence of cholangitis, history of previous chemotherapy and patients considered unsuitable for ERCP (e.g. severe heart, lung & kidney problems) were excluded from this study.The present study revealed that:There was no significant difference regarding age, sex between groups of benign and malignant biliary obstruction.