الفهرس 
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Abstract
Enterobacter isolates are important nosocomial and multidrug resistance pathogens responsible for serious nosocomial infections. They tend to contaminate various medical, intravenous, and other hospital devices. Nosocomial outbreaks have also been associated with the colonization of certain surgical equipments and operative cleaning solutions.
The aim of this work was to estimate the frequency of isolation of Enterobacter spp. as nosocomial pathogens, to study their antimicrobial resistance pattern with detection of ESβLs and MβLs, to detect biofilm-producing Enterobacter strains phenotypically and genotypically (FimH gene), and to assess the relation between the ability of biofilm production and antimicrobial drug resistance.
This study was conducted in Medical Microbiology and Immunology Department, Faculty of medicine, Menoufia University during the period from April 2017 to March 2018. Clinical samples (296) were collected and processed according to the standard microbiological methods. Enterobacter species identification was done using Vitek-2 compact system.
A total of 50 Enterobacter isolates were obtained from the different clinical samples. Enterobacter infections were more common among females (70%), patients aged from 30-60 years (36%), who stayed in hospitals more than 10 days (56%), admitted to ICU (54%), used antibiotics (98%), exposed to invasive procedures (100%) and had associated co-morbidities (96%).