الفهرس 
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Abstract
De Quervain’s tenosynovitis is a disease affecting tendons of the first extensor compartment of the wrist. It is common in the age group 30-50 years old, but it may affect teenagers who use their cell phones in texting messages frequently. It is affecting females more than males; the incidence of this disease among population is not known accurately until now.
Patients are complaining of pain, tenderness, limitation of motion and sometimes swelling over the radial styloid, radiating up to the forearm or to the thumb, positive finkelstein test is diagnostic. Treatment falls under two strategies: conservative treatment which is offered to patients as the first line of treatment (thumb spica, NSAIDs, physiotherapy and local injections) and surgical release of the 1st compartment.
Our study aims to determine the efficacy of the PRP in the treatment of de Quervain tendinopathy that induce self-healing of the tendons.
from March 2018 to September 2018, 20 patients with 21 wrists diagnosed as having de Quervain’s tenosynovitis were injected with PRP injection into the first dorsal compartment.
The age of the patients ranged from 19 to 58 years old with a Mean ± SD of 39.90 ± 12.57. The study included 11 patients with de Quervain’s tenosynovitis on the right side, 8 patients with symptoms on the left side and one patient with bilateral affection. In 66.7% of cases the dominant side was affected.
There were 16 females (80%) and 4 males (20%) with a ratio 4:1. house wives represented 50% of cases, students represented 5% of cases, office workers represented 20% of cases, and manual workers represented 25% of cases.
We withdrew a specific amount of venous blood (10 ml) from the patient and kept it in tubes containing anticoagulants. The double-spin centrifugal technique was used to separate and concentrate the platelets. The platelet count in the venous sample collected from the patient as well as in the final plasma product was used to calculate the concentration factor (ranging from 2.3-3.7). The total time from blood withdrawal to injection of the patients was about 30-45 minutes.
The affected wrist was rested comfortably with the elbow flexed and the forearm in mid-prone position. The point of most tenderness was identified by gentle palpation. The needle was introduced from distal to proximal at 45 degrees down to the flexor sheath. (1.5-2 ml) of PRP was injected evenly and slowly.
At the end of the follow up period of three months, patients were assessed according to DASH and VAS scores.
At the end of follow up, seventeen patients showed gradual improvement and significant decrease of their VAS and DASH scores from the baseline score. In the initial visit, patients had a mean VAS score of 75.0 ± 15.39 and a mean DASH score of 53.49 ± 13.72. Twelve weeks after the procedure, patients reported a mean improvement of 62.83% (75.0 to 28.5) in their VAS scores compared with the initial values; DASH scores had improved 53.24% (53.49 to 25.32).
None of the patients was recorded with any complication just after injection or at the end of the follow up period