الفهرس 
Chronic Kidney DiseaseOnly 14 pages are availabe for public view
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Abstract
T
here is a close relationship between CKD and increased risk for cardiovascular disease: major cardiac events actually represent almost 50% of the causes of death in CKD patients.
Chronic kidney disease patients, particularly those with end-stage renal disease are at much higher risk of cardiovascular disease than the general population.
Chronic renal dysfunction has a negative effect on cardiac function and chronic kidney disease is an important predictor of adverse outcome and increased morbidity in patients with chronic heart failure
There was a strong growing evidence that cardiac function and structure get worsen as the kidney function decline.
This study aims to study relationship between changes in cardiac structure and function among predialysis CKD patients and different clinical laboratory data.
This study included 60 adult patients with predialysis CKD, Patients with prior renal transplantation, advanced heart failure, chronic infection, malignancy, rheumtic or congenital heart disease were excluded.
All patients underwent clinical examination, laboratory investegations and echocardiography.
This study showed that 75% of patients were stage IV and 25% were stage IV.
Patients aged between 22 and 62 years mean age (51.7±9.7), the percentage of male sex to female sex was 86.7 %to 13.3%. Hypertension was the major cause of chronic kidney disease around 62%and second most common cause was Diabetes mellitus
Our results showed that about 36.7 % of patients were HCV positive while 65% were negative. About 71.7% of patients were anemic 33.3% had hypertriglycerides, 3.3% were hypocalcemic, 10% were hyperphosphatemic and 58.7% had microalbuminuria.36.7% had macroalbuminuria.
Hypertension is associated with increased cardiovascular risk in CKD.
Proteinuria is important risk factor for cardiac dysfunction.
Hypertension and proteinuria must be adjustably controlled to avoid cardiac complication.
In our study, 33.3% had diastolic dysfunction, 10% had systolic dysfunction, 16.7% had tricuspid regurge, 15% had mitral regurge, 3.3% had aortic valve sclerosis and 11.7% had septal hypertrophy.
Echocardiography is a crucial investigation for the assessment of LV structure and function and for the diagnosis of causes of HF, such as LVH, myocardial ischemia, valvular disease, and pericardial effusion or constriction also provide measurements of ventricular diameters and volumes, wall thickness, chamber geometry, ejection fraction (EF), and regional wall motion abnormalities.